NIA’s mission is to improve the health and well-being of … 1997 — The Resource Centers for Minority Aging Research are funded to investigate the variability of health differences experienced across racial and ethnic groups, as well as the mentoring of new scholars in health disparities research. Investigators explore how DNA interstrand crosslinks — very detrimental to cells — are removed from DNA and how this relates to age-associated disease. A wide variety of in vitro and in vivo models are employed to approach these issues. In addition, it coordinates the Intervention Testing Program using mice and the Caenorhabditis Intervention Testing Program using three species of Caenorhabditis. Email or call us for health or Alzheimer’s information. 15K likes. Get the latest public health information from CDC », Get the latest research information from NIH », NIH staff guidance on coronavirus (NIH Only) », National Advisory Council on Aging (NACA), Advances in Alzheimer's Disease & Related Dementias Research, NIA and the National Plan to Address Alzheimer's and Related Dementias. Of the 18 appointed members, 12 are leading representatives of health and scientific disciplines, including the fields of public health and behavioral or social sciences. Learn about NIA's role in leading the research effort for the National Plan. Using animal models and studies of human subjects, LNS investigators are discovering how factors such as dietary energy intake and exercise affect the brain during aging, and they are developing and testing novel interventions designed to optimize brain function throughout the lifespan. Access free clinical practice tools and training materials. Join the crowd—age can bring changes that affect your eyesight. The Institute on Aging is still providing seniors and adults living with disabilities much needed support during this time of COVID-19. AgePageNational Institute on Aging. Laboratory of Clinical Investigation (LCI) Our programs have been adjusted to meet the recommendations from the CDC and DPH, focusing on the health and safety of both our clients and staff. The branch supports all stages of clinical development for pharmacologic and non-pharmacologic interventions and combination therapies, as well as research on methods development and training for innovative trial design. National Institutes of Health Menopausal Hormone Therapy Information ... 440-442-7550 info@menopause.org www.menopause.org. National Institute on Aging Exercise and Physical Activity: Getting Fit for Life “My wife, Miki, and I have heart problems. 2014 — NIA’s 40th anniversary is celebrated at the Gerontological Society of America annual meeting in Washington, DC. Laboratory of Behavioral Neuroscience (LBN) 2006 — NIA leads the NIH conference “AD: Setting the Research Agenda a Century after Auguste D,” a conclave assessing the state of current Alzheimer's disease research and the most promising routes to progress. Find information on research into global trends in aging and aging-related diseases. Grants & Funding Sleep and Biological Rhythms encompasses age-related studies of epidemiology, etiology, pathogenesis, diagnosis, treatment and prevention of sleep disorders of older people; and of altered sleep-wake cycles/disordered biorhythmicity and their behavioral and neurodegenerative effects in the aged. Clinical Gerontology focuses on clinically related research on aging changes over the lifespan. NIA leads the federal effort supporting and conducting research on the biological, clinical, behavioral and social aspects of aging. Basic biologic research is examining genetic and other factors influencing aging, how they affect longevity and the development of age-related diseases. The goal is to promote exercise and physical activity nationwide for people 50 and older. The program now integrates labs and resources, bringing together those who share similar research interests from different vantage points. DEA manages NIA's grants and training policies and procedures, including oversight of grants and contract administration, scientific review and committee management functions. The focus was on how chronic diseases – specifically cancer, HIV/AIDS and diabetes – affect biological aging. NACA provides counsel on matters relating to the conduct and support of biomedical, social, and behavioral research; training; health information dissemination; and other programs regarding the aging process, diseases and other needs of the aging population. Explore tips to help a loved one with Alzheimer’s engage in holiday celebrations at home. With NIA leadership, GSIG organized and co-sponsored this conference with the Alliance for Aging Research and the Gerontological Society of America, with additional private sector support provided through the Foundation for the National Institutes of Health (FNIH). NIA and the Icelandic Heart Association announce collaboration on a vast study on the interactions of age, genes and the environment. Clinical Trials plans and administers clinical trials on age-related issues. Since 1974, the National Institute on Aging (NIA) mission has been to improve the health and well-being of older Americans through biomedical, social and behavioral research. Research in geriatrics is uncovering new ways to combat frailty and improve function with age. Training for researchers, clinicians, students. The third Geroscience Summit, organized by the trans-NIH Geroscience Interest Group, provide a forum for novel interactions between disease-focused professional societies and foundations, and the community of researchers and practitioners of geroscience. LMBI programs have a strong translational component with studies aimed at improving vaccine efficacy in the elderly and examining the molecular and cellular basis of tumor metastasis. The NIA Intramural Research Program is reorganized to recognize new paradigms in the field of aging research. The National Advisory Council on Alzheimer's Research, Care, and Services issued a final report from the first National Research Summit on Care, Services, and Supports for Persons with Dementia and Their Caregivers. New Study from the National Institute of Aging Interventions Testing Program (NIA ITP) Shows Protandim Significantly Extends Lifespan in Male Mice. ADORE resources include recruitment plans, communication materials, toolkits and guides, videos, and related research articles. Laboratory of Genetics and Genomics (LGG) National Plan to Address Alzheimer’s Disease, Alzheimer’s Disease Research Summit 2012: Path to Treatment and Prevention, International Alzheimer’s Disease Research Portfolio, NIH Toolbox for Neurological and Behavioral Function, Alzheimer’s Disease-Related Dementias: Research Challenges and Opportunities, Professional Judgment Budget for Alzheimer’s disease, Disease Drivers of Aging: 2016 Advances in Geroscience Summit, presented at the World Economic Forum Annual Meeting, in Davos Switzerland on “Curing Alzheimer’s: The Research Imperative.”, Alzheimer's Disease Research Implementation Milestone Database, Cognitive Aging Summit to Highlight Brain Resilience, Reserve. Population-level interventions and pragmatic trials to improve health, health delivery, quality of care, and to reduce health disparities as well as quasi-experimental techniques to identify causal effects where experiments are impractical or infeasible. This branch supports the full spectrum of drug discovery and preclinical drug development from target discovery and validation through securing Investigational New Drug status for small molecules and biologics aimed at prevention, treatment and management of individuals with or at-risk for cognitive decline, Alzheimer's disease and related dementias. The DGCG supports research on health and disease in older people and research on aging over the human lifespan, including its relationships to health outcomes. Within and across the branches, BSR supports research and initiatives on the familial, social, behavioral and economic factors pertaining to cognitive health and Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD) at both the population and individual levels. Designed in collaboration with the Alzheimer’s Association, the database captures the full spectrum of research investment and resources and enables public and private funders of Alzheimer’s research to share and review funding data. The group promotes discussion, sharing of ideas, and coordination of activities within the NIH research community, working on mechanisms underlying age-related changes, including those which could lead to increased disease susceptibility. This interactive quiz is a helpful tool to test your knowledge about the reality of aging. NIA, one of the 27 Institutes and Centers of NIH, leads a broad scientific effort to understand the nature of aging and to extend the healthy, active years of life. Immunology supports studies on changes in the immune systems of older people that affect health and may contribute to the increased incidence of infection including regulation of lymphocyte proliferation, immune specificity, autoimmune disease and other immunopathologies, endocrine control of immune function and interventions to retard and/or correct age-related decline in immune function. NIH, represented by NIA, participates in the federal Advisory Council on Alzheimer’s Research, Care, and Services. This has led to new and innovative ways to conduct research, share data and translate findings into practice. Dr. Hodes also directs the federal effort to find effective ways to treat or prevent Alzheimer's disease, as NIA is the lead NIH institute for this mission. The Study of Women's Health Across the Nation is launched to characterize in diverse populations the biological and psychosocial influences related to the transition to menopause. It also supports biological resource facilities that provide aged animals and banked tissues for use in aging research. DAB plans and supports molecular, cellular, genetic, interventional and systems biology research on the mechanisms of aging and age-related conditions. A central goal is the maintenance and development of research infrastructure for clinical trials and biomarkers development, which includes the national network of Alzheimer’s Disease Research Centers. The Division of Neuroscience, and this branch in particular, interact and collaborate with the Division of Behavioral and Social Research where psychological science and behavioral neuroscience converge, as well as with the Division of Geriatrics and Clinical Gerontology where aging of non-neural systems, geriatric syndromes and CNS function converge. BSR is committed to advancing high-caliber science in a variety of disciplines, including demography, lifespan development, psychology, behavioral medicine, behavioral economics, sociology, interpersonal relationships, health services research, behavioral genetics, and social epidemiology to promote the health and wellbeing of persons living with AD/ADRD and their caregivers. The mission of the National Institute of Nursing Research (NINR) is to promote and improve the health of individuals, families, communities, and populations. Further, LCI takes a multisystem approach to age-related changes because changes in one system lead to adaptive changes in another. 1993 — The first Edward Roybal Centers for Research on Applied Gerontology are authorized, focusing on translational research to convert basic and clinical findings into programs that improve the lives of older people and their families. About 2 years ago, we joined our local health club, where we do both endurance and strength-training exercises. Fundamental Neuroscience supports studies on age-related structural and functional changes in brain, including mechanisms of selective vulnerability and plasticity of neural cells, synapses, circuits and networks to neurodegeneration. IDEAL is a sub-study of the Baltimore function in late life to prevent disease and disability in a small but growing segment of the aging population. Find scientific resources and datasets. He is a diplomate of the American Board of Internal Medicine, a member of The Dana Alliance for Brain Initiatives, a fellow of the American Association for the Advancement of Science, and a member of the National Academy of Medicine at the National Academies of Sciences, Engineering, and Medicine. Programs cover fundamental biological questions such as: 1) the study of gene regulatory mechanisms that mediate cellular responses to developmental signals, immune activation and stress stimuli; 2) induction of effective immune responses, including the mechanisms of class switch recombination and somatic hypermutation, and generation and maintenance of memory; 3) the role of telomere length and telomerase activity in lymphocyte function and aging; and 4) immune regulatory mechanisms that affect aging. May 31, 1974 — Public Law 93-296 authorizes the establishment of a National Institute on Aging and mandates the Institute develop a national comprehensive plan to coordinate the U.S. Department of Health, Education, and Welfare (succeeded by the Department of Health and Human Services) involvement in aging research. 2019 — NIA’s 45th anniversary is celebrated at the Gerontological Society of America annual meeting in Austin, Texas. NIA leads the formation of the Trans-NIH GeroScience Interest Group. The National Institute on Ageing is a Ryerson University think tank focused on the realities of Canada’s ageing population. Researchers investigate the genes and gene expression programs that govern the physiologic declines of aging (e.g., reduced strength, menopause, decreased ability to respond to nutrient imbalances, and diminished immune function) and the increased pathologies of the elderly (e.g., neurodegeneration, cardiovascular disease, diabetes, arthritis, obesity and cancer). 99-660, section 501-503, authorizes NIA's Alzheimer's Disease Education and Referral (ADEAR) Center as part of a broad program to conduct research and distribute information about Alzheimer's disease to health professionals, patients and their families, and the general public. Research focuses on discovery of novel genomic elements and their functional roles driving heterogeneity and pathogenesis of AD. Launched in 1958, the BLSA is the most comprehensive and longest running longitudinal examination of human aging in the world. Endocrinology supports basic research into the causes and effects of age-related changes in the endocrine system, and on aging-dependent changes in cellular responses to endocrine factors. Data from these studies are available to qualified researchers, subject only to restrictions imposed for some linked administrative data. NIA, with other institutes and the private sector, cosponsors the Alzheimer’s Disease-Related Dementias: Research Challenges and Opportunities Summit, led by the National Institute of Neurological Disorders and Stroke (NINDS). 2004 — NIA launches the Longevity Consortium, a network of investigators from several large-scale human cohort studies working in collaboration with individual basic biological aging researchers to facilitate the discovery, confirmation and understanding of genetic determinants of healthy human longevity. Laboratory of Cardiovascular Science (LCS) PSP supports research and data infrastructure development projects on how demographic, social, economic, institutional, geographic and other factors at the population level influence health and mortality at older ages. BSR’s research portfolio in AD/ADRD includes the areas of dementia care, caregiver research, cognitive and dementia epidemiology, behavioral and social pathways, early psychological changes, prevention, health disparities, and research resources. The collaboration extends 34 years of data on the health of 23,000 Icelandic residents into the new millennium. The Accelerating Medicines Partnership (AMP) is launched. This includes research on mechanisms of behavior change and behavioral interventions, cognitive and emotional functioning, molecular and behavior genetics, sociogenomics, technology and human factors, family and interpersonal relationships, and integrative biobehavioral research on the mechanistic pathways linking social and behavioral factors to health in mid-life and older age. LMG has found a signaling pathway from nuclear damage to mitochondrial dysfunction, which seems to be defective in some DNA repair defective disorders including Alzheimer’s disease, and intervention with nicotinamide adenine dinucleotide supplementation has beneficial effects. NIAGADS is the National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site. Looking for advice about healthy aging? Research is supported on the genetic, molecular, cellular and neural mechanisms underlying changes in the brain and its interaction with other physiological systems. Read about NIA's intramural research and scientists. National Research Summit on Care, Services, and Supports for Persons with Dementia and Their Caregivers. Research to elucidate the psychological, behavioral and interpersonal mechanisms that account for later life health inequalities is particularly encouraged, as is research that elucidates causal pathways underlying successful aging and resilience. The National Institute on Aging (NIA) is one of 27 Institutes and Centers of the National Institutes of Health (NIH), a component of the U.S. Department of Health and Human Services. October 7, 1974 — The National Institute on Aging is established. Tissue Physiology supports research on the integrated physiology of multiple organ systems that affect aging, as well as the age-related changes specific to the function of each of several specific organ systems. The workshop focused on such conditions as Lewy body dementia, frontotemporal dementia, and vascular dementia. Another focus is on how these tissues interact in the context of overall health to establish an integrated physiology of healthy aging. DAB chairs the Trans-NIH Geroscience Interest Group (GSIG) that includes representation from 20 NIH Institutes and Centers. To understand Motor Function, research is supported on proprioception, postural control and balance, neuromuscular function, sensory-motor integration and movement disorders in aging, including Parkinson's disease. NIA launches the International Alzheimer’s Disease Research Portfolio. Studies are designed to integrate knowledge and identify common behavioral and biologic pathways of disease and function related to the cardiovascular, neuro-cognitive, musculoskeletal, body composition and metabolic systems, and investigate how these are affected by age, health disparities, socioeconomic status, genetic difference and modifiable risk factors. Since its founding in 1974, NIA research has changed the way America understands aging. Mandated by Congress to inform legislators of the strategy and resources needed to meet research goals of the National Plan to Address Alzheimer’s Disease, this “bypass budget” suggests the amount of additional funds needed in Fiscal Year 2017 to accelerate the pace of discovery leading to prevention or treatment of Alzheimer’s by 2025. En español Send us your comments. NIA scientists and other experts review this content to ensure it is accurate and up to date. Print Publications Efforts also focus on translation to clinical trials of our findings based on observational studies. NIA also has a broad information program to communicate about research and health with older people, their families, health professionals, researchers, policymakers and others. 2016 — The Trans-NIH GeroScience Interest Group with essential collaboration and support from the New York Academy of Sciences, American Federation of Aging Research, and Gerontological Society of America, developed the “Disease Drivers of Aging: 2016 Advances in Geroscience Summit”, at the request of the research community. NIA announces the Fiscal Year 2020 Professional Judgment Budget for Alzheimer’s disease. Interdisciplinary research with connections to biological, genetic, psychological, behavioral and interpersonal factors to better understand social and population processes influencing health and aging. NIA organizes the Alzheimer’s Disease Research Summit 2012: Path to Treatment and Prevention. As a leading researcher in the field of immunology, Dr. Hodes was named NIA director in 1993. LCS goals are to: 1) identify age associated changes that occur within the cardiovascular system and to determine the mechanisms for these changes; 2) determine how aging of the heart and vasculature interacts with chronic disease states to enhance the risk for CV diseases in older persons; 3) study basic mechanisms in excitation-contraction coupling and how these are modulated by surface receptor signaling pathways in cardiac cells; 4) elucidate mechanisms of pacemaker activity in sinoatrial nodal cells; 5) elucidate mechanisms that govern cardiac and vascular cell survival; and 6) establish the potentials and limitations of new therapeutic approaches such as changes in lifestyle, novel pharmacologic agents or gene or stem cell transfer techniques in aging or disease states. September is designated as Go4Life Month in collaboration with the White House Conference on Aging. Mission. This scheme assigns cases to high, intermediate, or low likelihood categories that the dementia is due to AD. 2000 — NIA distributes established mouse cDNA microarray/clone set containing more than 15,000 unique genes to 10 designated academic centers worldwide. Research emphases include healthy aging across the lifespan (including exceptional longevity); protective factors against multiple age-related conditions; determinants of rates of progression of age-related changes that affect disease risk, particularly those for multiple age-related conditions; menopause and mid-life aging changes; translational human research to follow up findings from basic research on aging; long-term effects of current or new interventions that may be administered over a large part of the lifespan; and long-term effects of physical activity throughout the lifespan. You are visiting the NIA publications ordering portal. Surgeon General, the President’s Council on Fitness, Sports and Nutrition, and other national, state and local partners. LNS has a focus on signal transduction pathways that control the development and adult plasticity of nerve cell circuits, and how these pathways are affected by dietary energy intake and exercise in the contexts of aging and neurological disorders. Get information on applying for funding from NIA. Global Aging Find information on research into global trends in … OD also responds to analytical requests from stakeholders within and outside of NIH regarding NIA’s extramural grant operations, including subjects such as the Next Generation Researchers Initiative. Research emphases include multifactorial geriatric syndromes such as falls, frailty, and various types of disability; effects of comorbidity and polypharmacy; effects of age-related changes on clinical or functional disease outcomes or treatment responses; effects of physical activity on disease and disability in older persons; and the elucidation, diagnosis, and treatment of previously unappreciated pathologic changes in old age (e.g., sarcopenia, vascular stiffening, diastolic dysfunction). November 14, 1986 — P.L. 1992 — NIA and the University of Michigan begin the Health and Retirement Study, which follows more than 20,000 people at 2-year intervals, providing data from pre-retirement to advanced age to enable multidisciplinary study of the causes and course of retirement. National Institute on Aging (NIA): One of the US National Institutes of Health (NIH). 2008 — NIA convenes a Biology of Aging Summit to review its research portfolio, identify areas of opportunity, and facilitate formulation of comprehensive research plans for the future. Alzheimer’s disease research implementation milestones, Alzheimer's & Dementia Outreach, Recruitment & Engagement Resources (ADORE), Together We Make the Difference: National Strategy for Recruitment and Participation in Alzheimer’s and Related Dementias Clinical Research. Collaborations with the NIA Division of Geriatrics and Clinical Gerontology include the influence of childhood factors on aging outcomes, and research on pain, subjective well-being, and resilience in aging. The relationship between sensory or motor dysfunction and age-related dementia is a developing area. 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